Gradient

TECH-SOLUTION ENGINEERING

At TPN we are using cutting-edge technologies such as AI & ML, Blockchain & Crypto, IoT, 3D Printing and many others to build tech-based products & solutions either for our own sake or for our valued customers by means of our all-in-one tech-solution, Ascend by TPN.

Here is an overview of the core technologies we are using at TPN to engineer deep tech-solutions for our life sciences & healthcare customers :

NEXT-GEN ARTIFICIAL INTELLIGENCE & MACHINE LEARNING

The bottom line, the entire platform is currently powered by AI-driven algorithms (search engines, key words based matchmaking,...) that uses Deep Learning as well as Supervised & Reinforcement Learning techniques and quality datasets.

Our current models are consequently built, trained, and tested in a smart, fast and secure way without requiring an immense computing power nor a great amount of data.


However, as far as real world data & real world uncertainty are concerned, we are moving towards next-gen AI & models that use probabilistic programming as well as the Bayesian statistics which is the key to adjust parameters to see what they actually are (posteriors) are and thus make predictions as accurately as possible. Indeed, we want to use probabilistic & Bayesian models, and plenty of other methods & techniques to be able read a large variety of Entreprise data, interpret & summarize them, and make appropriate predictions to help companies rapidly adapt as their business & customers evolve. 

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BLOCKCHAIN & CRYPTO

Our Blockchain-based platform includes decentralized application (dApp) that is built on public Ethereum Blockchain. Transactions on our dApp, Zefir™ platform, will be using either Fiat (8% fees), Ethereum (3% fees) or our own utility tokens / TXP (0% fees). Zefir™ platform (MVP) is currently Ethereum cryptocurrency and will be the 3 aforementioned means of payment.

As a consequence of that, users will have the ability to freely chose one of these means of payment and thus have the possibility to eliminate high fees & purchase services, all in a simple & efficient manner.

INTERNET OF THINGS

This technology concerns connected equipments, men & material tracking, sample lifecycle management, smart packaging, and cold chain monitoring are among the IoT applications that are particularly well suited to healthcare organizations & pharmaceuticals company. With the help of our partners, here is our offer to our customers :

INCREASING MANUFACTURING EFFICIENCY

• Smart equipment that collects operational data and status (run time, temperature, load, ready to use/in operation/under

  cleaning/under maintenance)

• Add sensor packs to collect device data & build a back-end platform using industrial IoT platforms

• Run analytics on the data to predict when a piece of equipment might shut down

• Automate incident requests triggered by integration with ticket management systems

• Sensors that collect metadata for analysis to identify and reduce causes of process variability and improve production yield

• Visibility into human and material movement across the workshop through tracking and monitoring technologies.

TRACKING PRODUCTS IN THE WAREHOUSE

Increase Operational Efficiency in the Warehouse

• Sensors on product/holding items transmit information on product location, inventory and inconsistencies directly to the

  warehouse manager’s handheld device/ dashboard

• The device uses sensor data to simulate a real-time, 3-D view of the warehouse

• Embedded sensor packs on forklifts track their location and utilization

• A wireless reader captures data (volume, dimensions) transmitted from pallets as they arrive

Maintain Desired Storage Conditions

• Environmental sensors collect data in temperature-controlled areas of the warehouse to track drugs’ environmental conditions

  in real time

• Active and passive logger data is compared with thermo stability tables to generate alerts in the event of temperature

  excursions

​​Align Production & Demand

Sensors collect and analyze data on shipment movements – from the warehouse, to distribution, to production planning.

TRACKING PRODUCTS AT EVERY POINT

Ensure Product Integrity & Traceability Across the Supply Chain

• 2-D bar codes, RFID tags and smart labels for packaging

• NFC sensors for drug and vaccines packaging

• Electronic circuit/chip for packaging material

• Packaging data transmitted throughout the transport of drugs and during drug dispensing

• Data collected in the central system transmitted over private or public cloud to assure traceability and inform decision making.

Optimize Inventory Costs Among Supply Chain Partners

• 2-D Bar codes, RFID tags and smart labels used in packaging

• Transmitters at warehouses capture consignment movement and report to central location

• Inventory and supply chain decisions leverage real-time information on product movement to ensure optimal stock levels

TEMPERATURE SPIKES MANAGEMENT & DRUG QUALITY MAINTENANCE DURING TRANSPORT

• Embed environmental sensors inside product packages / pallets in shipment containers to continually track the temperature

  of drugs

• Employ program sensors to automatically signal alerts if vaccine storage moves outside a specified temperature range

  whether during removal from a refrigerated environment to a shipping container, or due to a refrigeration malfunction

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3D-PRINTING

The first 3D-printed prescription drugs clearly illustrate the potential of 3D printing to radically change the pharmaceutical industry, making this technology the new heavyweight player in Big Pharma. With its extreme versatility and inherent ability to customize products, we strongly believe that 3D printing will finally blow the field of affordable personalized medicine wide open. 

We are offering our customers solutions that consist in the 3D printing of containers for pharmaceutical packaging & logistics with or without a tracking system (IoT). We are relying on but not limited to the following 3D drug printing techniques :

SELECTIVE LASER SINTERING (SLS) PRINTING

  • Using a laser to turn a powder into solid pieces. We can incorporate drugs into the powder to produce drug-loaded printed drugs

SEMISOLID EXTRUSION (SE) PRINTING

  • Turning a semisolid material into chewable tablets which is very useful in pediatric and geriatric patients

FUSED DEPOSITION MEDOLING (FDM)

  • Melting a feedstock of extruded polymer to construct an object at layer-by-layer basis, such as a pharmaceutical-grade polymer that can be loaded with active(s) ingredient(s) to create modified release medicines

STEREOLITHOGRAPHY (SLA) PRINTING

  • Using a laser to turn a liquid material into solid parts, such a polymer that can also be loaded with active(s) ingredient(s)

TABLETS DESIGN

  • Using CAD software to design tablets for further to printing band. We thus can manufacture medicines of any geometry

CLOUD COMPUTING

We are using the cloud for a wide variety of tech-based solutions. It provides services/features including compute, storage, databases, artificial intelligence & machine learning, IoT, security, and much more for implementing innovation, automation, and continuous deployments. Our provider is also chosen for its commitment to making those services compliant with global health data regulations, which is key component for us.

We are using the cloud for a wide variety of tech-based solutions. It provides services/features including compute, storage, databases, artificial intelligence & machine learning, IoT, security, and much more for implementing innovation, automation, and continuous deployments. Our provider is also chosen for its commitment to making those services compliant with global health data regulations, which is key component for us.